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- DS Network, Inc. - See how you can make a difference in the lives of individuals with Down syndrome. DSNetwork advocates for oppportunities for individuals with DS so they may fully participate in society.
- Down Syndrome - www.Dspn.org - Includes a list of service providers, also books to consider reading.
- Central Illinois Down Syndrome Organization - Contains a list of the organization's goals, and information about their library and events.
- Search Directory Page - Includes information on clinical studies, a scrapbook, upcoming events, and newsletter.
- Gold Coast Down Syndrome Org. - In Palm Beach county, FL. Provides a FAQ and inclusion information.
- Connecticut Down Syndrome Congress - The Connecticut Down Syndrome Congress Website.
- Down's Syndrome Association, Liverpool Branch - Read back issues of their newsletter.
- Down Syndrome Research Online Advocacy Group - Information on clinical, biomedical, and scientific research into Down syndrome.
- Eastern Pennsylvania Down Syndrome Center - Includes a message board and chat room, also a list of their coming events.
- Association of Greater Cincinnati for Down Syndrome - The Down Syndrome Association of Greater Cincinnati provides information, resources and support to individuals with Down syndrome, their families, and their communities
- Ventura County, CA Down Syndrome Support Group - Parent & Family Support Group for Ventura County California.
- Down Syndrome Association of Toronto - DSAT is a not profit organization provides support and information to parents parents of children with Down syndrome, students and teachers.
- Triangle Down Syndrome Network - For families in central North Carolina. Online newsletter and stories about their kids.
- Alzheimer - www.ProudOnline.org - Parents Regional Outreach for Understanding Down Syndrome, based in Orange County, California.
- Down Syndrome Research Foundation - Articles on psychological, social, and physical development, also on health issues. Research project reports and summaries.
- Down's Syndrome Association - London Branch - UK - Support group for parents and carers of people with Down's Syndrome.
- Hawkeye Area Down Syndrome Association - Resources and support for individuals, families, professionals in the Iowa City area affected by Down Syndrome. We hope to enhance the quality of life for all individuals with Down Syndrome.
- Mile High Down Syndrome Association - Mile High Down Syndrome Association (MHDSA) Home page. Information for new parents of babies with Down Syndrome, free educational seminars and support groups, special events & social activities, resources, and an Adult Down Syndrome clinic.
- Ups & Downs Calgary Down Syndrome Association - The Calgary Ups & Downs Society supports families with a child or children with Down syndrome

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